BDBM429784 5-[3-[4-(4- chloro-2- methoxy- phenyl)-1- piperidyl]-2- methyl-3-oxo- propyl]-5- (methoxymethyl) imidazolidine- 2,4-dione::US10550100, Compound 108
SMILES COC[C@]1(C[C@H](C)C(=O)N2CCC(CC2)c2ccc(Cl)cc2OC)NC(=O)NC1=O
InChI Key InChIKey=XXQLCMDLJMBMLB-ZSEKCTLFSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 429784
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: 75nMAssay Description:The basis for the assay is the cleavage of the substrate 5FAM-LAQAVRSSSRK-5TAMRA (SEQ ID No 3) (Anaspec, custom 34891) by human TACE (R&D SYSTEMS INC...More data for this Ligand-Target Pair